Faculty members located in academic
departments/centers can be formally associated with the IGBB in two
different ways:
1. IGBB Fellows
Through its Fellows Program, the
IGBB rewards those faculty who have worked within the IGBB to build a
strong, vibrant molecular biosciences/computational biology research
community at MS State. IGBB Fellows receive not only formal recognition
for their accomplishments, but they are given a voice in many aspects of
IGBB operation including, but not limited to, input on purchases, new hires,
and overall research direction. The IGBB Fellows literally serve as
the Director's Advisory Committee. To be an IGBB Fellow, a faculty member from an academic department
must (1) regularly submit proposals through the IGBB, (2) have had at least one funded external grant (with overhead)
administered through the IGBB, (3) have a record of high-impact scientific
productivity, and (4) have a national/international reputation in his/her
field. IGBB Fellows have full "internal user" access to the HPC² supercomputers and receive HPC²
computer, technical, and administrative support.
2. IGBB Faculty Affiliates
An IGBB Faculty Affiliate is any faculty member in an MS State academic department who (1) conducts research
in the molecular biosciences and/or computational biology and (2) collaborates in some manner with IGBB faculty/staff. Like IGBB Fellows, IGBB Faculty Affiliates are encouraged to submit proposals through the IGBB, but
are not obligated to do so. IGBB Faculty Affiliates generally do not
have HPC² supercomputer access unless they are working on an IGBB
research project. Faculty Affiliates can request access to the HPC²
supercomputers if they are interested in generating data/results for an eventual proposal submission
through the IGBB. Any IGBB Faculty Affiliate that submits and receives an external grant (with
overhead) through the IGBB will be eligible for the IGBB Fellows Program.
Developmental potential of bovine oocytes cultured in different maturation and culture conditionsIGBB Authors:
Erdogan MemiliPUBLICATION YEAR:
2007IMPACT FACTOR:
2.012CITATION COUNT:
71Sagirkaya H, Misirlioglu M, Kaya A, First NL, Parrish JJ, Memili E (2007) Developmental potential of bovine oocytes cultured in different maturation and culture conditions.
Animal Reproduction Science 101(3-4): 225-240.
DOI:
10.1016/j.anireprosci.2006.09.016EID:
2-s2.0-34547124097PMID: 17052869
DOWNLOAD PDFABSTRACTDiverse groups of chemicals in culture media are needed for successful bovine oocyte maturation and embryo development during which dramatic cytoplasmic and nuclear reprogramming events take place. In vitro embryo production (IVP) procedures frequently include supplements such as serum and/or co-culture with various types of somatic cells. However, the presence of undefined serum in culture media introduces a variation from batch to batch, increases viral or prion contamination risk, and leads to problems during fetal development. The aim of the present study was to investigate the possibility of using chemically defined-synthetic serum substitute (SSS) in place of fetal calf serum (FCS) during maturation and long-term culture to stimulate in vitro maturation (IVM), fertilization (IVF) and subsequent embryo development. In Experiment I, the effect of the protein source on in vitro maturation was tested by maturing oocytes in culture media supplemented with 10% FCS (Control Group), 10% SSS (Group I) and 10% SSS+10 ng/ml epidermal growth factor (EGF) (Group II). In Experiment II, effects of SSS on both oocyte maturation and embryo development during in vitro culture (IVC) were tested by maturing oocytes in media supplemented with 10% FCS (FCS Group) or 10% SSS+10 ng/ml EGF (SSS Group), followed by IVF and IVC in SOF media supplemented with 10% FCS and 10% SSS on day 4 for FCS and SSS Groups, respectively. Even though rates for cleavage and development to blastocyst stage were not different, blastocyst cell numbers were higher in Group II containing SSS and EGF. The SSS supplementation group had higher apoptotic nuclei as compared to the FCS Group in Experiment II. Transcripts for heat shock protein 70 (Hsp70), interferon tau (IF-tau), DNA methyltransferase 3a (Dnmt3a), desmosomal glycoprotein desmocollin III (DcIII) and insulin-like growth factor II receptor (Igf-2r) were altered in different culture conditions in Experiment I. However, only glucose transporter-1 (Glut-1) mRNA was different in the SSS and FCS Groups in the second experiment. In summary, SSS and EGF in maturation medium and replacement of FCS with SSS alone in culture medium on day 4 of IVC support oocyte maturation and embryo development in vitro. However, significance of culture condition induced changes on the genome-wide abundance of messenger ribonucleic acid and the significance of the apoptotic nuclei during fetal development still remain to be determined.
Dr. Matthew W. 
BrownAssociate Professor
IGBB Fellow
website (662) 325-2406
Dr. Bindu Nanduri
Professor
IGBB Fellow
(662) 325-4217
Dr. Zhaohua Peng
Professor
IGBB Fellow
(662) 325-0685
Dr. Hossam Abdelhamed
Assistant Research Professor
IGBB Affiliate
(662) 325-1125
Dr. Pratima 
Acharya AdhikariAssistant Professor
IGBB Affiliate
website (662) 325-3416
Dr. Peter J. Allen
Professor
IGBB Affiliate
(662) 325-4768
Dr. Ashli Brown
Professor
IGBB Affiliate
(662) 325-3324
Dr. Sam Chang
Professor
IGBB Affiliate
(662) 325-3200
Dr. Wen-Hsing Cheng
Professor
IGBB Affiliate
(662) 325-3200
Dr. Sandra B. 
CorreaAssistant Professor
IGBB Affiliate
website (662) 325-0158
Dr. Angus Dawe
Professor
IGBB Affiliate
(662) 325-7577
Dr. Thu 
DinhAssociate Professor
IGBB Affiliate
website (662) 325-7554
Dr. Peixin Fan
Assistant Professor
IGBB Affiliate
(662) 325-0963
Dr. Jean M.N. Feugang
Associate Research Professor
IGBB Affiliate
(662) 325-7567
Dr. Christine Fortuin
Assistant Professor
IGBB Affiliate
(662) 325-0282
Dr. Esteban Galeano
Assistant Professor
IGBB Affiliate
(662) 325-7782
Dr. Austin Himes
Assistant Professor
IGBB Affiliate
(662) 325-4249
Dr. Federico G. 
HoffmannAssociate Professor
IGBB Affiliate
website (662) 325-2763
Dr. Attila Karsi
Professor
IGBB Affiliate
(662) 325-0405
Dr. Margaret L. Khaitsa
Professor
IGBB Affiliate
(662) 325-1365
Dr. William Kingery
Professor
IGBB Affiliate
(662) 325-2311
Dr. Andrew 
KoubaProfessor
IGBB Affiliate
website (662) 325-2378
Dr. Natraj (Krish) Krishnan
Associate Professor
IGBB Affiliate
(662) 325-2978
Dr. Mark Lawrence
Professor
IGBB Affiliate
(662) 325-1205
Dr. Caleb Lemley
Associate Professor
IGBB Affiliate
(662) 325-2934
Dr. Shien Lu
Professor
IGBB Affiliate
(662) 325-3511
Dr. Benjamin 
MagbanuaAssociate Professor
IGBB Affiliate
website (662) 325-9777
Dr. Florencia Meyer
Associate Professor
IGBB Affiliate
(662) 325-7734
Dr. Ramakrishna (Rama) Nannapaneni
Research Professor
IGBB Affiliate
(662) 325-7697
Dr. Diana Outlaw
Associate Professor
IGBB Affiliate
(662) 325-4803
Dr. E. David Peebles
Professor
IGBB Affiliate
(662) 325-3379
Dr. Andy 
PerkinsProfessor
IGBB Affiliate
website (662) 325-0004
Dr. Sorina Popescu
Associate Professor
IGBB Affiliate
(662) 325-7735
Dr. Lauren 
PriddyAssistant Professor
IGBB Affiliate
website (662) 325-5988
Dr. Stephen B. Pruett
Professor
IGBB Affiliate
(662) 325-6653
Dr. K. Raja 
ReddyResearch Professor
IGBB Affiliate
website (662) 325-9463
Dr. John 
RigginsProfessor
IGBB Affiliate
website (662) 325-2984
Dr. Leyla 
Rios de AlvarezAssistant Professor
IGBB Affiliate
website (662) 325-2802
Dr. Sejo Sabanadzovic
Professor
IGBB Affiliate
(662) 325-9322
Dr. Michael Sandel
Assistant Professor
IGBB Affiliate
(662) 325-3133
Dr. Wes Schilling
Professor
IGBB Affiliate
(662) 325-9456
Dr. Keun-Seok Seo
Associate Professor
IGBB Affiliate
(662) 325-1419
Dr. Xueyan Shan
Associate Research Professor
IGBB Affiliate
(662) 325-2640
Dr. Rubin Shmulsky
Professor
IGBB Affiliate
(662) 325-2243
Dr. Juan L. 
SilvaProfessor
IGBB Affiliate
website (662) 325-3200
Dr. C. Beth Stokes
Associate Professor
IGBB Affiliate
(662) 325-5811
Dr. Justin 
ThorntonAssociate Professor
IGBB Affiliate
website (662) 325-8020
Dr. Te-Ming (Paul) Tseng
Associate Professor
IGBB Affiliate
(662) 325-4725
Dr. Carrie 
VanceAssociate Research Professor
IGBB Affiliate
website (662) 325-2640
Dr. Guiming Wang
Professor
IGBB Affiliate
(662) 325-0414
Dr. Mark 
WelchProfessor
IGBB Affiliate
website (662) 325-7564
Dr. Li 
ZhangAssistant Research Professor
IGBB Affiliate
website (662) 325-3416
Dr. Xue 
ZhangAssistant Research Professor
IGBB Affiliate
website (662) 325-3200
Former Fellows & Affiliates (Position with IGBB; Current Institution)
Jeffrey F.D. Dean (Affiliate; University of Georgia)
Jonas King (Affiliate)
Hongxu Dong (Affiliate; Goldman Sachs, Atlanta)
Terezie Tolar-Peterson (Affiliate; California State University, San Bernadino)
Erdogan Memili (Affiliate; Prairie View A&M University)
Gregory Bohach (Affiliate; retired)
Brian A. Counterman (Affiliate; Auburn University)
Renita Horton (Affiliate; University of Houston)
Xiu-feng "Henry" Wan (Affiliate; University of Missouri)
Din-Pow Ma (Affiliate; retired)
David A. Ray (Fellow; Texas Tech University)
Shane C. Burgess (Fellow & former IGBB Director; University of Arizona)
Fiona M. McCarthy (Fellow; University of Arizona)
Susan M. Bridges (Fellow; retired)
Susan V. Diehl (Affiliate; retired)
James N. Warnock (Affiliate; University of Georgia)
Dragica Jeremic Nikolic (Affiliate; University of Toronto)
Cetin Yuceer (Affiliate; Turkey)
The IGBB is supported, in part, by the following units:
The IGBB is an HPC² member center.