The IGBB logo features a stylized "pinwheel" to the left of the letters IGBB in caps in a modified Bank Gothic Pro font.
The six-part "pinwheel" in the IGBB logo is:
- A symbol of lab unity as it shows "parts" coming together to make a "whole."
- A flower or three-leaf clover representing (a) plants, important subjects of our research, (b) life in general, and (c) the life sciences (biology).
- A set of chromosomes being moved towards the center of a cell.
- The Sun - another symbol of life.
- A protein composed of six subunits (e.g., a protein pore).
- Three foxes putting their heads together. The fox is a symbol of cleverness in Western folklore. Since the IGBB is organized into three service groups (Genomics, Proteomics/Metabolomics, and Biocomputing/Computational Biology), the foxes could represent the three disciplines working together.
- A scientist jumping for joy after making an important discovery.
- A windmill, the primary symbol associated with Cervantes' famous character Don Quixote - Like Don Quixote, scientists must be willing to attack 'wicked giants' (e.g., ignorance, racism, sexism, intolerance, use of the term 'science' in the promotion of non-scientific causes), champion worthy causes (e.g., education, intellectual freedom, human rights, environmental responsibility), and remain optimistic in the face of defeat (e.g., most days in the lab). Hopefully, however, the average scientist can accomplish these tasks without becoming delusional (a problem that squashed Quixote's dreams of becoming a plant molecular biologist).
- A DNA double-helix or protein in cross section.
- Antibodies binding to a protein.
- Whatever you want it to be.

Mark A. Arick, II (Tony)Interm Director & Computer Specialist
BIOCOMPUTING LEAD
email(662) 325-0583
Pace 110

Proteome and phosphoproteome dynamic change during cell dedifferentiation in Arabidopsis
IGBB Authors:
Zhaohua PengPUBLICATION YEAR:
2007IMPACT FACTOR:
6.144CITATION COUNT:
52Chitteti BR, Peng Z (2007) Proteome and phosphoproteome dynamic change during cell dedifferentiation in Arabidopsis.
Proteomics 7(9): 1473-1500.
DOI:
10.1002/pmic.200600871EID:
2-s2.0-34248640306PMID: 17407188
DOWNLOAD PDFABSTRACTCell dedifferentiation is a cell fate switching process in which a differentiated cell reverts to a status with competence for cell division and organ regeneration like an embryonic stem cell. Although the phenomenon of cell dedifferentiation has been known for over two and a half centuries in plants, little is known of the underlying mechanisms. Here, we have established the proteome map of Arabidopsis cotyledons and investigated the dynamic change of the cotyledon proteome in the time course of cell dedifferentiation. Among the 353 distinct genes, corresponding to 500 2-DE gel protein spots identified with high confidence, 12% have over twofold differential regulations within the first 48 h of induction of cell dedifferentiation. The distributions of these genes among different Gene Ontology categories and gene differential regulations within each of the categories have been examined. In addition, we have investigated the cotyledon phosphoproteome using Pro-Q Diamond Phosphoprotein in Gel Stain followed by mass spectrometry analyses. Among the 53 identified putative phosphoproteins, nine are differentially regulated during cell dedifferentiation. These studies have provided significant new insight into protein and phosphoprotein differential expression during cell dedifferentiation in plants.
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The IGBB is an HPC² member center.