Proteomics & Metabolomics

In addition to doing work on existing IGBB projects, the IGBB proteomics staff can perform a variety of mass spectrometry and other proteomics services for MS State principal investigators and IGBB collaborators. Such research can be performed through a Proposal Partnership, a Research Agreement, or the Service Center.

The IGBB's proteomics staff has considerable expertise in...

Protein isolation/purification from all types of organisms/tissues
1D & 2D gel electrophoresis
Gel- and non-gel-based mass spectrometry
Protein identification
Discovery and characterization of post-translational modifications;
Quantitative proteomics
Comparative proteomics & metabolomics
Western blotting & protein visualization
Integration of proteomic and nucleic acids data (e.g., proteogenomic mapping)
Functional annotation of proteins using Gene Ontology (GO) standards and procedures

With regard to mass spectrometers, the IGBB's proteomics staff utilizes a ThermoFisher LTQ Orbitrap Velos, a Waters Nano ESI Q-TOF (model Xevo G2-S), and an Applied Biosystems (now ThermoFisher) MALDI TOF TOF. The LTQ Orbitrap Velos and the Nano ESI Q-TOF are fitted with upstream HPLC sample purification systems.

To discuss the possibility of having the IGBB conduct proteomics research in collaboration with you, please submit a ticket through the MyIGBB HelpDesk. An IGBB proteomics consultant will respond to your query as quickly as possible (usually within 24 hours).

A listing of IGBB Standard Services and their prices -- including information and prices for Training and Self-Service Equipment Usage -- is available in the Standard Services Catalog in MyIGBB and in PDF form via the link below.

Price List

ALSO SEE: Genomics (including Transcriptomics) | Biocomputing (Bioinformatics & Computational Biology)

NOTE: PIs are asked to consider whether the participation of an IGBB employee in a project merits that employee's inclusion as a co-author on a resulting manuscript(s). The decision ultimately lies with the PI. However, the IGBB encourages IGBB staff and faculty involved in Proposal Partnerships and Research Agreements to discuss/negotiate co-authorship with PIs before starting work on a project.

Agricultural & Biological Engineering Animal & Dairy Sciences Biochem., Mol. Biol., Entomol. & Plant Pathol. Chemistry Forestry Plant & Soil Sciences Sustainable Bioproducts

Agricultural Economics Basic Sciences (CVM) Biological Sciences Food Sci., Nutrition & Health Promotion Pathobiol. & Population Med. (CVM) Poultry Science Wildlife, Fisheries & Aquaculture

Michelle Latham
Accounting Assistant
PURCHASING
email
(662) 325-4075

The Gene Ontology: Enhancements for 2011

High Impact Research

IGBB Authors:
Teresia J. Buza, Shane C. Burgess, Catherine R. Gresham, Fiona M. McCarthy

PUBLICATION YEAR: 2012
IMPACT FACTOR: 8.808
TIMES CITED (as of August 10, 2017): 153
CITATION PERCENTILE: 99

Blake JA, Dolan M, Drabkin H, Hill DP, Ni L, Sitnikov D, Burgess S, Buza T, Gresham C, McCarthy F, Pillai L, Wang H, Carbon S, Lewis SE, Mungall CJ, Gaudet P, Chisholm RL, Fey P, Kibbe WA, Basu S, Siegele DA, McIntosh BK, Renfro DP, Zweifel AE, Hu JC, Brown NH, Tweedie S, am-Faruque Y, Apweiler R, Auchinchloss A, Axelsen K, Argoud-Puy G, Bely B, Blatter MC, Bougueleret L, Boutet E, Branconi-Quintaje S, Breuza L, Bridge A, Browne P, Chan WM, Coudert E, Cusin I, Dimmer E, Duek-Roggli P, Eberhardt R, Estreicher A, Famiglietti L, Ferro-Rojas S, Feuermann M, Gardner M, Gos A, Gruaz-Gumowski N, Hinz U, Hulo C, Huntley R, James J, Jimenez S, Jungo F, Keller G, Laiho K, Legge D, Lemercier P, Lieberherr D, Magrane M, Martin MJ, Masson P, Moinat M, O'Donovan C, Pedruzzi I, Pichler K, Poggioli D, Porras Millan P, Poux S, Rivoire C, Roechert B, Sawford T, Schneider M, Sehra H, Stanley E, Stutz A, Sundaram S, Tognolli M, Xenarios I, Foulger R, Lomax J, Roncaglia P, Camon E, Khodiyar VK, Lovering RC, Talmud PJ, Chibucos M, Gwinn Giglio M, Dolinski K, Heinicke S, Livstone MS, Stephan R, Harris MA, Oliver SG, Rutherford K, Wood V, Bahler J, Lock A, Kersey PJ, McDowall MD, Staines DM, Dwinell M, Shimoyama M, Laulederkind S, Hayman T, Wang SJ, Petri V, Lowry T, D'Eustachio P, Matthews L, Amundsen CD, Balakrishnan R, Binkley G, Cherry JM, Christie KR, Costanzo MC, Dwight SS, Engel SR, Fisk DG, Hirschman JE, Hitz BC, Hong EL, Karra K, Krieger CJ, Miyasato SR, Nash RS, Park J, Skrzypek MS, Weng S, Wong ED, Berardini TZ, Li D, Huala E, Slonim D, Wick H, Thomas P, Chan J, Kishore R, Sternberg P, Van Auken K, Howe D, Westerfield M (2012) The Gene Ontology: Enhancements for 2011. Nucleic Acids Research 40(D1): D559-D564.

DOI: 10.1093/nar/gkr1028
EID: 2-s2.0-84859699831
PMID: 22102568

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ABSTRACT
The Gene Ontology (GO) (http://www.geneontology.org) is a community bioinformatics resource that represents gene product function through the use of structured, controlled vocabularies. The number of GO annotations of gene products has increased due to curation efforts among GO Consortium (GOC) groups, including focused literature-based annotation and ortholog-based functional inference. The GO ontologies continue to expand and improve as a result of targeted ontology development, including the introduction of computable logical definitions and development of new tools for the streamlined addition of terms to the ontology. The GOC continues to support its user community through the use of e-mail lists, social media and web-based resources.

More High Impact Research

The IGBB is supported, in part, by the following units:

Missisippi Agricultural & Forestry Experiment Station - MAFES

Office of Research & Economic Development - ORED

Division of Agriculture, Forestry & Veterinary Medicine - DAFVM

The IGBB is an HPC² member center.