Proteomics & Metabolomics

In addition to doing work on existing IGBB projects, the IGBB proteomics staff can perform a variety of mass spectrometry and other proteomics services for MS State principal investigators and IGBB collaborators.  Such research can be performed through a Proposal Partnership, a Research Agreement, or the Service Center.

The IGBB's proteomics staff has considerable expertise in...

  • Protein isolation/purification from all types of organisms/tissues
  • 1D & 2D gel electrophoresis
  • Gel- and non-gel-based mass spectrometry
  • Protein identification
  • Discovery and characterization of post-translational modifications;
  • Quantitative proteomics
  • Comparative proteomics & metabolomics
  • Western blotting & protein visualization
  • Integration of proteomic and nucleic acids data (e.g., proteogenomic mapping)
  • Functional annotation of proteins using Gene Ontology (GO) standards and procedures

With regard to mass spectrometers, the IGBB's proteomics staff utilizes a ThermoFisher LTQ Orbitrap Velos, a Waters Nano ESI Q-TOF (model Xevo G2-S), and an Applied Biosystems (now ThermoFisher) MALDI TOF TOF. The LTQ Orbitrap Velos and the Nano ESI Q-TOF are fitted with upstream HPLC sample purification systems.

To discuss the possibility of having the IGBB conduct proteomics research in collaboration with you, please submit a ticket through the MyIGBB HelpDesk.  An IGBB proteomics consultant will respond to your query as quickly as possible (usually within 24 hours).

A listing of IGBB Standard Services and their prices -- including information and prices for Training and Self-Service Equipment Usage -- is available in the Standard Services Catalog in MyIGBB and in PDF form via the link below.

ALSO SEE: Genomics (including Transcriptomics) | Biocomputing (Bioinformatics & Computational Biology)

NOTE: PIs are asked to consider whether the participation of an IGBB employee in a project merits that employee's inclusion as a co-author on a resulting manuscript(s). The decision ultimately lies with the PI. However, the IGBB encourages IGBB staff and faculty involved in Proposal Partnerships and Research Agreements to discuss/negotiate co-authorship with PIs before starting work on a project.

Affiliated Departments
Employee Spotlight

Natalie Young
Research Administrator
(662) 325-3670

High Impact Research
Proteomic analysis using an unfinished bacterial genome: the effects of subminimum inhibitory concentrations of antibiotics on Mannheimia haemolytica virulence factor expression

High Impact Research

IGBB Authors:
Bindu Nanduri, Mark L. Lawrence, Shane C. Burgess


The IGBB is supported, in part, by the following units:

The IGBB is an HPC² member center.