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IGBB News & Research Highlights

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July 22, 2015

Dr. Matthew Brown, a faculty member in Biological Sciences and an IGBB Fellow, was recently honored as the College of Arts & Sciences Researcher of the Month. In July 2014 Dr. Brown published a paper describing a new species of protist, and on June 1, 2015, Dr. Brown received a grant from the National Science Foundation for his proposal "Examining The Macroevolutionary Trajectories in Amoebozoa, A Major Lineage of Eukaryotes." Dr. Brown's successful NSF proposal was submitted through the IGBB and involves use of the High Performance Computing Collaboratory (HPC²) supercomputers. The IGBB is an HPC² Member Center.

For more information click here.

April 21, 2015

The Institute for Genomics, Biocomputing & Biotechnology (IGBB) continues its run of high profile publications with an April 20, 2015 paper in the journal Nature Biotechnology. The article “Sequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement” is co-authored by IGBB director Dr. Daniel G. Peterson (click here for article). Of note, Nature Biotechnology has a Thomson Reuters journal impact factor of 39.080. Of the 8539 journals that Thomson Reuters indexes, only twenty (i.e., 0.23%) have impact ratings greater than 30. The IGBB’s cotton Nature Biotechnology paper represents the eighth time the institute has had a publication with an impact factor over 30 since 2009.

As for the scientific value of the research described in the Nature Biotechnology paper, Peterson says, “Gossypium hirsutum, commonly known as upland cotton, is the cotton species grown commercially in Mississippi and throughout most of the cotton-growing regions of the world. It is the upland cotton DNA sequence that will ultimately be of most use to cotton breeders, farmers, and scientists looking to keep cotton plants healthy and productive." Peterson notes that the importance of cotton genetic resources is especially relevant today with climate change and invasive pest species jeopardizing the productivity of the cotton industry.

In addition to his role as IGBB director, Peterson is a professor in the Department of Plant & Soil Sciences.

The IGBB is a university-wide institute jointly governed by the Mississippi Agricultural and Forestry Experiment Station, the College of Veterinary Medicine, the Division of Agriculture, Forestry and Veterinary Medicine, and the Office of Research and Economic Development. Additionally, the IGBB is a member of MSU’s High Performance Computing Collaboratory. For more on the research, contact Peterson at or visit the IGBB website at

January 30, 2015

From Mississippi State University News--Recent findings that shed new light on ancient and modern connections between dinosaurs, crocodiles and birds have Mississippi State scientists playing important roles as the research moves forward.

Publication of three reports in the Dec. 12 issue of Science describing work of the university researchers is drawing international attention. The investigations focused on the evolution of birds, dinosaurs and their closest living relatives, the Australian saltwater crocodile, American alligator and Indian gharial.

Science, a weekly report by the American Association for the Advancement of Science, is considered the world's leading journal of original research, global news and commentary.

"Comparisons between species were made at the genome/DNA level affording unprecedented insight into how crocodilians and birds have diverged," explained Daniel G. Peterson, director of MSU's Institute for Genomics, Biocomputing and Biotechnology, or IGBB, for short.

The genome is the genetic material of an organism.

The crocodilian genome initiative is led by David Ray, a former MSU assistant professor of biochemistry, molecular biology, plant pathology and entomology who also holds the rank of IGBB Fellow.

The genome research is made possible by a National Science Foundation grant proposed by Peterson and Ray.

Ray is senior and corresponding author of the Science article titled "Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs." Peterson and Federico Hoffman, an IGBB researcher and MSU assistant professor of biochemistry, molecular biology, entomology and plant pathology, are co-authors.

A second article dealt with avian evolution made possible through comparative genomics. Titled "Comparative genomics reveals insights into avian genome evolution and adaptation," it is co-authored by Hoffman and Ray.

Ray, now an associate professor of biological sciences at Texas Tech University, wrote the third article, titled "Whole-genome analyses resolve early branches in the tree of life of modern birds." In it, he uses genome-scale analysis to determine the history of modern birds.

Peterson said he and his colleagues take great pride that MSU is "represented on three genome papers in a single issue of Science." He also noted that previously "we have had papers on the genomes of sorghum, cotton, butterfly and green anole publish in Nature, a journal that is every bit as prestigious as Science."

The professor of plant and soil sciences said the string of publications "in two of the highest impact scientific journals illustrates Mississippi State's growing footprint in genomics and computational biology research."

For the complete article, click here.
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Recent Publications

Kook I, Henley C, Meyer F, Hoffmann FG, Jones C (2015) Bovine herpesvirus 1 productive infection and immediate early transcription unit 1 promoter are stimulated by the synthetic corticosteroid dexamethasone. Virology 484: 377-385.
PMID: 26226582
DOI: 10.1016/j.virol.2015.06.010

Su W, Wang C, Luo J, Zhao Y, Wu Y, Chen L, Zhao N, Li M, Xing C, Liu H, Zhang H, Chang YF, Li T, Ding H, Wan X, He H (2015) Testing the Effect of Internal Genes Derived from a Wild-Bird-Origin H9N2 Influenza A Virus on the Pathogenicity of an A/H7N9 Virus. Cell Reports 12(11): 1831-1841.
PMID: 26344762
DOI: 10.1016/j.celrep.2015.08.029

Ferguson L, Eckard L, Epperson WB, Long LP, Smith D, Huston C, Genova S, Webby R, Wan XF (2015) Influenza D virus infection in Mississippi beef cattle. Virology 486: 28-34.
PMID: 26386554
DOI: 10.1016/j.virol.2015.08.030

Sun H, Cunningham FL, Harris J, Xu Y, Long LP, Hanson-Dorr K, Baroch JA, Fioranelli P, Lutman MW, Li T, Pedersen K, Schmit BS, Cooley J, Lin X, Jarman RG, DeLiberto TJ, Wan XF (2015) Dynamics of virus shedding and antibody responses in influenza A virus-infected feral swine. Journal of General Virology 96(9): 2569-2578.
PMID: 26297148
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Nho SW, Abdelhamed H, Reddy S, Karsi A, Lawrence ML (2015) Identification of high-risk Listeria monocytogenes serotypes in lineage I (serotype 1/2a, 1/2c, 3a and 3c) using multiplex PCR. Journal of Applied Microbiology 119(3): 845-852.
PMID: 26095922
DOI: 10.1111/jam.12876

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