The IGBB is a member of the NIH-funded Mississippi IDeA Network of Biomedical Research Excellence (Mississippi INBRE or MS-INBRE), a program designed to build biomedical infrastructure throughout the state. Through MS-INBRE, Mississippi students and faculty at Mississippi's undergraduate institutions are (1) trained in biomedical research techniques, (2) given the opportunity to work with top researchers at Mississippi's major research universities, (3) afforded access to state-of-the-art bioscience equipment, and (4) provided with assistance in preparing grant proposals. The IGBB serves as the MS-INBRE proteomics/computational biology core. For more information about MS-INBRE, click here.
Dr. George V. PopescuAssistant Research Professor
FACULTY
email(662) 325-7369
Pace 118
Efficient capture of unique sequences from eukaryotic genomes
IGBB Authors:
Daniel G. PetersonPUBLICATION YEAR:
2002IMPACT FACTOR:
7.986CITATION COUNT:
64Peterson DG, Wessler SR, Paterson AH (2002) Efficient capture of unique sequences from eukaryotic genomes.
Trends in Genetics 18(11): 547-550.
DOI:
10.1016/S0168-9525(02)02764-6EID:
2-s2.0-0036843242PMID: 12414178
DOWNLOAD PDFABSTRACTCot-based cloning and sequencing (CBCS), a synthesis of Cot analysis, DNA cloning and high-throughput sequencing, promises to accelerate the study of eukaryotic genomes. In particular, CBCS will (1) permit efficient gene discovery in species with substantial quantities of repetitive DNA, (2) allow the sequence complexity (i.e. all the unique sequence information) of large genomes to be elucidated at a fraction of the cost of shotgun sequencing, and (3) enhance genome sequencing efforts by facilitating capture of low-copy sequences not secured by EST sequencing. CBCS should accelerate comparative genomics research, especially in large genomes such as those of many crops.
The IGBB is supported, in part, by the following units:
The IGBB is an HPC² member center.
