The IGBB is a member of the NIH-funded Mississippi IDeA Network of Biomedical Research Excellence (Mississippi INBRE or MS-INBRE), a program designed to build biomedical infrastructure throughout the state. Through MS-INBRE, Mississippi students and faculty at Mississippi's undergraduate institutions are (1) trained in biomedical research techniques, (2) given the opportunity to work with top researchers at Mississippi's major research universities, (3) afforded access to state-of-the-art bioscience equipment, and (4) provided with assistance in preparing grant proposals. The IGBB serves as the MS-INBRE proteomics/computational biology core. For more information about MS-INBRE, click here.
Dr. George V. PopescuAssistant Research Professor
FACULTY
email(662) 325-7369
Pace 118
The remarkable evolutionary history of endornaviruses
IGBB Authors:
Sead SabanadzovicPUBLICATION YEAR:
2011IMPACT FACTOR:
3.61CITATION COUNT:
62Roossinck MJ, Sabanadzovic S, Okada R, Valverde RA (2011) The remarkable evolutionary history of endornaviruses.
Journal of General Virology 92(Pt 11): 2674-2678.
DOI:
10.1099/vir.0.034702-0EID:
2-s2.0-80053955800PMID: 21775577
DOWNLOAD PDFABSTRACTThe family Endornaviridae contains several members from diverse hosts, including plants, fungi and oomycetes. They are found as large dsRNA elements with a nick in the coding strand. All members encode a conserved RNA-dependent RNA polymerase, but no other domain that is conserved among all members. Based on the conserved domain database comparison the various domains have different origins, indicating a highly modular evolutionary history. In some cases, domains with similar putative functions are found that are derived from different protein families, indicating convergent evolution for a required function.
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